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Exonization of AluYa5 in the human ACE gene requires mutations in both 3’ and 5’ splice sites and is facilitated by a conserved splicing enhancer -- Lei et al. 33 (12): 3897 -- Nucleic Acids Research
●04/17 22:14
Haixin Lei ,Ian N. M. Day ,7,396Total Views 7,3967,152 Pageviews244 PDF DownloadsDecoding the complex journeys of RNAs along neuronsNonequilibrium hybridization-driven CRISPR/Cas adapter with extended energetic penalty for discrimination of single-nucleotide variantsRapid discovery of functional RNA domainsSystematic genetic perturbation reveals principles underpinning robustness of the epigenetic regulatory networkSingle-stranded DNA drives σ subunit loading onto mycobacterial RNA polymerase to u

Identification and analysis of alternative splicing events conserved in human and mouse -- Yeo et al. 102 (8): 2850 -- Proceedings of the National Academy of Sciences
●04/16 16:27
Research ArticleJune 11, 2018Neural network retuning and neural predictors of learning success associated with cello trainingIn sophisticated auditory–motor learning such as musical instrument learning, little is understood about how brain plasticity develops over time and how the related individual variability is reflected in the neural architecture. In a ...The auditory and motor neural systems are closely intertwined, enabling people to carry out tasks such as playing a musical instrument whos

The SWISS-PROT protein knowledgebase and its supplement TrEMBL in 2003 -- Boeckmann et al. 31 (1): 365 -- Nucleic Acids Research
●04/15 23:21
19,167Total Views 19,16717,037 PageviewsApril 2025 20Cryo-EM structures of DNA-free and DNA-bound BsaXI: architecture of a Type IIB restriction–modification enzymeTranscriptional induction by ecdysone in Drosophila salivary glands involves an increase in chromatin accessibility and acetylationMaternal histone mRNAs are uniquely processed through polyadenylation in a Stem-Loop Binding Protein (SLBP) dependent mannerAutophagy induction enhances homologous recombination-associated CRISPR–Cas9 gene editi

Localization of mitochondrial DNA base excision repair to an inner membrane-associated particulate fraction -- Stuart et al. 33 (12): 3722 -- Nucleic Acids Research
●04/13 18:50
7,342Total Views 7,3426,945 PageviewsApril 2025 6Chromatin-associated α-satellite RNA maintains chromosome stability by reestablishing SAF-A in the mitotic cell cycleOxidative stress at telomeres triggers internal DNA loops, TRF1 dissociation, and TRF2-dependent R-loopsNuclear AGO2 supports influenza A virus replication through type-I interferon regulationTailoring and reversing m6A editing with sequential RNA bioorthogonal chemistryPoly-(ADP-ribose) serves as a scaffold for the methyltransferase ME

Genetic Suppression of Intronic +1G Mutations by Compensatory U1 snRNA Changes in Caenorhabditis elegans -- Zahler et al. 167 (4): 1689 -- Genetics
●04/12 08:23
Living in poverty is associated with gene expression changes in immune cells

Intron Retention: A Common Splicing Event within the Human Kallikrein Gene Family -- Michael et al. 51 (3): 506 -- Clinical Chemistry
●04/05 19:06
AI Discovery AssistantADLM JournalsADLM JournalsADLM JournalsAI Discovery AssistantLatest IssueVolume 71 Issue 4April 2025Latest Open Access ArticleA Meta-Analysis and Systematic Review of Cardiac Troponin I vs T in Community Dwelling Adults: Is Specificity at Risk?Yashika Parashar and othersClinical Chemistry, hvaf023, https://doi.org/10.1093/clinchem/hvaf023Background Cardiac troponin I and T measured by high-sensitivity assays (hs-cTn) are detectable in most ambulatory adults. Hs-cTnI and T m

Large-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serum -- Welsh et al. 100 (6): 3410 -- Proceedings of the National Academy of Sciences
●04/04 08:25
Sustainable Development GoalsSustainable Development GoalsSustainable Development GoalsResearch ArticleBiological SciencesFree accessShare onLarge-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serumJohn B. Welsh, Lisa M. Sapinoso, Suzanne G. Kern, +11 , David A. Brown, Tao Liu, Asne R. Bauskin, Robyn L. Ward, Nicholas J. Hawkins, David I. Quinn, Pamela J. Russell, Robert L. Sutherland, Samuel N. Breit, Christopher A. Moskaluk, Henry F. Frierson, Jr., and Garret

Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans -- Lewis et al. 100 (1): 189 -- Proceedings of the National Academy of Sciences
●04/04 05:31
Sustainable Development GoalsSustainable Development GoalsSustainable Development Goals

Organelle Proteomics: Implications for Subcellular Fractionation in Proteomics -- Huber et al. 92 (9): 962 -- Circulation Research
●03/08 13:31
Site maintenance Monday, March 10, 2025. Please note that new registrations and purchases will be unavailable on this date.

Aberrant and Alternative Splicing in Cancer -- Venables 64 (21): 7647 -- Cancer Research
●01/26 12:59
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