▽Nature Immunology ●11/21 21:25 UBXN9 governs GLUT4-mediated spatial confinement of RIG-I-like receptors and signalingWang and colleagues show that in skeletal muscle cells and cardiomyocytes, the glucose transporter GLUT4 is a negative regulator of RIG-I-like receptor signaling during viral infection by redistributing RIG-I and MDA5 to the plasma membrane and attenuating interferon responses.Andrew G. HarrisonDuomeng YangPe
▽The Journal of Immunology ●11/21 07:05 Issue 111 December 2024Top ReadsIgG Glycosylation: Biomarker, Functional Modulator, and Structural ComponentIgG Glycosylation: Biomarker, Functional Modulator, and Structural Component
▽Science Magazine Home ●11/21 03:02 20 Nov 2024Light-powered catalysts destroy ‘forever chemicals’
▽Nature: Science articles and news, scientific information and jobs: nature journal ●11/21 01:34 Superconductivity researcher who committed misconduct exits universityThe University of Rochester has confirmed that it no longer employs Ranga Dias, who was found by investigators to have committed data fabrication.Dan GaristoHow students and grandparents could solve the global mental-health crisisAfrican researchers piloted a slew of innovative, low-cost programmes for addressing the troubli
▽The Journal of Experimental Medicine ●11/20 21:55 | November 19 2024Purinergic control of innate-like T-cell survivalCalvin Xu et al.Xu et al. reveal that the ARTC2–P2RX7 regulatory axis is a key modulator of unconventional T-cell survival. Their findings show how this pathway selectively influences innate-like, IFN-γ and IL-4 co-producing T cells, providing insights into immune regulation during tissue damage.Article| November 19 2024New i