▽The Journal of Experimental Medicine ●05/15 00:29 Brief Definitive Report| May 13 2025DNGR-1 impacts pre-cDC migration and localizationAna Cardoso et al.Cardoso et al. show that DNGR-1–deficient pre-cDCs display cell-intrinsic alterations in their ability to colonize peripheral organs. Their findings highlight an unexpected role for innate immune receptors in regulating cDCpoiesis.People & Ideas| May 13 2025Laura Mackay: Don't be afraid to
▽Nature Immunology ●05/14 13:27 Inhibition of ENT1 relieves intracellular adenosine-mediated T cell suppression in cancerMetabolites in the tumor microenvironment, including adenosine, have been shown to suppress anti-tumor immune responses. Here, the authors show that T cell expression of the adenosine transporter ENT1 is involved in this immunosuppression and can be targeted to boost T cell function, tumor killing and immune
▽Science Magazine Home ●05/14 13:16 Science Signaling13 May 2025Unedited AMPARs scale upLucy PetersonRichard CocaReduced RNA editing of an AMPA receptor subunit increases synaptic activity in stimulus-deprived neurons.Science Translational Medicine7 May 2025A clinical trial of an adenoviral group B meningococcal vaccineByChristina DoldBlanch〓 Ogutiet al.Science Immunology9 May 2025Chimeric autoantibody receptor T cells t
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