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すべて | Journal
Engram mechanisms of memory linking and identity
Many cognitive functions rely on the ability to link distinct but related memories, while retaining the capacity to recall the individual details of the linked memories. Inokuchi and colleagues describe evidence that memory linking involves engram overlap and discuss the mechanisms that regulate this process.
Ali Choucry
Masanori Nomoto
Kaoru Inokuchi
Review Article25 Apr 2024
The molecular determinants of microglial developmental dynamics
The developmental colonization of the brain by microglial progenitors and establishment of microglial cell identity set the stage for microglial function in the adult. Barry-Carroll and Gomez-Nicola describe the mechanisms that regulate the development of microglia, including their origins, infiltration and colonization of the brain, proliferation and fate determination.
Liam Barry-Carroll
Diego Gomez-Nicola
Review Article24 Apr 2024
Skill switching
The main direction of motor skill-specific informatio
Research Articles, Behavioral/Cognitive
7-Tesla evidence for columnar and rostral–caudal organization of the human periaqueductal gray response in the absence of threat: a working memory study.
Alexandra K. Fischbach, Ajay B. Satpute, Karen Quigley, Philip A. Kragel, Danlei Chen, Marta Bianciardi, Larry Wald, Tor D. Wager, Ji-Kyung Choi, Jiahe Zhang, Lisa Feldman Barrett and Jordan E. Theriault
Journal of Neuroscience 25 April 2024, e1757232024; DOI: https://doi.org/10.1523/JNEUROSCI.1757-23.2024
Research Articles, Neurobiology of Disease
Differential activation states of direct pathway striatal output neurons during L-DOPA-induced dyskinesia development.
David A. Figge, Henrique de Amaral Oliveira, Jack Crim, Rita M. Cowell, David G. Standaert and Karen L. Eskow Jaunarajs
Journal of Neuroscience 25 April 2024, e0050242024; DOI: https://doi.org/10.1523/JNEUROSCI.0050-24.2024
Research Articles, Cellular/Molecular
Calcium-dependent regulation of neuronal excitability is rescued in Fragil
Cortical gene expression architecture links healthy neurodevelopment to the imaging, transcriptomics and genetics of autism and schizophrenia
Gene expression in the human cortex is shown to involve three general components, which reflect metabolic and immune programs of healthy development, and link case–control imaging and transcriptomics to genetic risk for autism and schizophrenia.
Richard Dear
Konrad Wagstyl
Petra E. Vértes
ArticleOpen Access22 Apr 2024
Identification of senescent, TREM2-expressing microglia in aging and Alzheimer’s disease model mouse brain
Neuroinflammation and microglia significantly contribute to Alzheimer’s disease pathology, depending on their activation state. We found that TREM2-expressing microglia are a heterogenous population spanning activated to senescent cells.
Noa Rachmian
Sedi Medina
Michal Schwartz
Article18 Apr 2024
Messenger RNA transport on lysosomal vesicles maintains axonal mitochondrial homeostasis and prevents axonal degeneration
Using human
How to freeze a memory: putting worms on ice stops them forgetting
The model organism Caenorhabditis elegans is quick to forget a notable odour — unless it is chilled or given lithium.
Australia’s Great Barrier Reef is ‘transforming’ from repeated coral bleaching
The coral reef is currently experiencing its worst mass bleaching event on record — warming waters brought on by climate change are to blame.
Bianca Nogrady
News19 Apr 2024
Will AI accelerate or delay the race to net-zero emissions?
As artificial intelligence transforms the global economy, researchers need to explore scenarios to assess how it can help, rather than harm, the climate.
Amy Luers
Jonathan Koomey
Eric Horvitz
Comment22 Apr 2024
How volcanoes shaped our planet — and why we need to be ready for the next big eruption
Heather Handley
Book Review22 Apr 2024
How to freeze a memory: putting worms on ice stops them forgetting
Julian Nowogrodzki
News22 Apr 2024
Your perception of time is skewed by what you see
Lilly T
Journal*
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YearVolume*Issue*Page/eLocation ID*
Report
Remyelination by surviving oligodendrocytes is inefficient in the inflamed mammalian cortex
Mezydlo et al.
Published online: April 17, 2023
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